Apache

APACHE is an innovative research project, funded by the European Research Council (ERC) and led by Dr. Cristina Canal

Apache

APACHE is an innovative research project, funded by the European Research Council (ERC) and led by Dr. Cristina Canal
Institution: UPC
Research group: Biomaterials, Biomechanics and Tissue Engineering group (BBT)
Principal investigator: Cristina Canal

The Problem

Primary bone cancer is a rare disease. However, it arises mainly in children and young adolescents, and despite the current therapies, mortality rate is still around 50%. Bone metastatic disease, usually incurable, also has serious clinical manifestations (pain, fragile bones, etc.), which makes this devastating cancer complication an important and costly health issue. Current therapy for primary bone cancers usually includes tumor resection followed by chemotherapy and/or radiotherapy. In some cases, these surgeries associate limb amputation and even when it is not the case, most patients that undergo limb-sparing surgery need reconstructive surgery to regain limb function. Chemotherapy associated side effects, risks and limitations of current treatment options highlight a significant unmet need.
APACHE is developing a novel therapy for bone cancer by taking advantage of the active species generated by cold Plasmas in combination with biomaterials to deliver the active species locally to the diseased site.

The Solution

The Solution

APACHE is developing a novel therapy for bone cancer by taking advantage of the active species generated by cold Plasmas in combination with biomaterials to deliver the active species locally to the diseased site.

Purpose

A novel solution that will allow to simultaneously treat bone cancer, while fostering bone regeneration.
Time to market: 10 years
Looking for: Investment for the preclinical regulatory and the clinical phase
Technology: Others
Area: Therapeutics
TRL: 3